AI RESEARCH
SpliceBind: Isoform-Aware Prediction of Binding Pocket Druggability
arXiv CS.LG
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ArXi:2606.04020v1 Announce Type: cross Splice-mediated drug resistance occurs in up to 40% of patients on targeted kinase inhibitors, yet state-of-the-art druggability tools operate on single structures and cannot compare across isoforms. We