AI RESEARCH
Enhancing Protein-Protein Interaction Prediction with Hierarchical Motif-based Multimodal Protein Embedding
arXiv CS.LG
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ArXi:2606.02629v1 Announce Type: cross Protein-protein interactions (PPIs) are essential for many biological processes. However, existing PPI prediction approaches suffer from two major limitations: they overlook the hierarchical organization of proteins, particularly meso-scale motifs that critically regulate PPIs, and fail to effectively integrate sequence, structure, and function modalities.