AI RESEARCH
Computational Modeling of Antibody-Antigen Complexes: PLM-Based and MSA-Based Approaches
arXiv CS.LG
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ArXi:2605.28886v1 Announce Type: cross Antibodies play a central role in the immune response by specifically recognizing and neutralizing antigens, and therapeutic antibodies have become major drugs for cancer and autoimmune diseases. However, their discovery still relies on extensive in vitro screening, and accurate computational modeling of antibody structures and antibody-antigen interactions can prioritize candidates, reduce experimental burden, and accelerate rational design.